Mucosal changes and inflammation around fillings and crowns, such as oral lichen, may be due to an allergic reaction to metals found in alloys used in dentistry. Replacement of fillings in metal-sensitive patients often leads to the disappearance of symptoms. Allergic reactions to metals used in dental restorations, pins, implants, prostheses and braces can be measured wit MELISA.
Symptoms may not always be local but can be systemic and include inflammation throughout the body. Patients with known clinical metal sensitivity such as adverse reactions to gold and nickel-containing jewellery should consider non-metallic restorative materials.
MELISA can provide information if the patient is reacting to any dental materials in his or her mouth. In some cases amalgam is not the problem, but gold in crowns or palladium in bridges. Together with a special metal-biopsy test, a dentist can pinpoint the exact restoration that contains the metal or metals to which the patient is reacting. This may save a lot of time and money if the patient has many different types of oral restoration.
MELISA can also be used as a preventive screening before the insertion of, for example, gold crowns or titanium implants. If an allergy is diagnosed the patient might consider biocompatible materials such as ceramics or zirconium.